The semi-prep SFC has capacity for larger scale purification, but can still be used for analytical scale method development. The autosampler accommodates 20 ml vials in 40 well plates. It is configured with Advion-expression Mass detector to allow two-dimensional analysis of complex chiral and achiral mixtures. The stacked injection set up allows multiple injections in a single sequence, the open-bed fraction collector can be triggered on time, threshold or slope based on signals from 2 different detectors signals including UV and/or MS. The macro cyclone separators provide simple gas-liquid separation in the fraction bottle for fraction recoveries typically greater than 95%.
Semi-Prep Features
Using supercritical carbon-dioxide and a co-solvent (methanol, isopropanol), this system offers rapid analysis and isolation. Fitted with three 1 cm columns that are:
Water Torus 2-PIC achiral column
Waters Torus 1-AA achiral column
Chiral Technologies IC immobilized column
More information about these columns and their uses can be found here.